Tadalafil 25 mg/ml Sublingual Drops - Customized Care | Bayview Pharmacy

Images are for illustration purposes only;
actual packaging may vary.

The Tadalafil 25 mg/ml Oral Sublingual Drops is a meticulously crafted liquid formulation designed specifically for patients requiring tadalafil in an easy-to-administer sublingual format. This preparation is conveniently dispensed in a user-friendly dropper bottle, providing precise and controlled dosing tailored to individual needs. The sublingual administration ensures rapid absorption and an expedited onset of action by bypassing the gastrointestinal tract, making it ideal for those who may have difficulties swallowing tablets or capsules, such as pediatric patients or those affected by dysphagia.

Tadalafil is recognized as a phosphodiesterase type 5 (PDE5) inhibitor, utilized primarily for the treatment of erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). The sublingual method of administration may offer a more convenient and potentially faster-acting alternative to oral tablets for patients suffering from these various conditions. Tadalafil works by relaxing the blood vessels in the penis, increasing blood flow and facilitating an erection in response to sexual stimulation. For PAH, it aids in relaxing blood vessels in the lungs, reducing pulmonary blood pressure and improving exercise capacity. The 25 mg/ml concentration provides flexibility in dosing, which can be personalized to cater to each patient’s response and tolerance regarding the medication.

A collection of satisfied patients' faces who have benefited from our services.

A symbol representing the custom formulation process, featuring a mortar and pestle with ingredients being mixed.

Custom sliders illustrating ingredient adjustments made for personalized formulations.

Symbol of user customization displayed through adjustable gears.

This medication is not available at retail pharmacies as it is specially compounded, making it more effective in meeting your unique therapeutic needs.

Medisca Logo

Dosing Calculator

A small arrow pointing down.

Utilize our dosing calculator for general dosing information tailored to your patient’s needs.

Formula Information

A small arrow pointing down.

The Tadalafil 25 mg/ml Oral Sublingual Drops is a specialized liquid formulation designed expressly for sublingual administration, facilitating rapid absorption and an expedited onset of action. This formulation is dispensed in a convenient dropper bottle, allowing for precise dosing and ensuring ease of use. The sublingual method is particularly advantageous for patients who face challenges swallowing conventional tablets or capsules, such as pediatric patients or those suffering from dysphagia. Moreover, the sublingual administration circumvents the gastrointestinal tract, mitigating the effects of first-pass metabolism and significantly enhancing the bioavailability of the active ingredient.

Tadalafil, a well-known phosphodiesterase type 5 (PDE5) inhibitor, is primarily indicated for treating erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Acting within the framework of ED, tadalafil works by relaxing the blood vessels in the penis, enabling increased blood flow, thereby facilitating an erection in response to sexual arousal. For patients with PAH, tadalafil alleviates pulmonary blood pressure by relaxing the blood vessels in the lungs, consequently improving symptoms such as shortness of breath and fatigue. The 25 mg/ml concentration allows clinicians to fine-tune the dosing for each patient based on their individual response and tolerance to the medication.

It's vital for both patients and prescribers to acknowledge that while tadalafil is effective for these conditions, it should be utilized carefully in patients with pre-existing cardiovascular disease and is contraindicated for individuals concurrently taking nitrates due to the risk of significant hypotension. Additionally, potential side effects may include headache, flushing, dyspepsia, and dizziness. As with any medication, adherence to the prescribed treatment regimen and monitoring for efficacy and adverse effects are critical in achieving optimal therapeutic results.

In the case that prescribers consider this formulation for their patients, it is essential to deliver comprehensive instructions on the proper use of the dropper bottle, highlighting the importance of taking the medication as advised. Patients should be counseled to place the drops beneath the tongue and allow the solution to dissolve without swallowing for maximum absorption. Should you have any inquiries or require additional information about Tadalafil 25 mg/ml Oral Sublingual Drops, do not hesitate to contact us at Bayview Pharmacy. Our dedicated team of expert compounding pharmacists is committed to providing support and guidance to ensure the safe and effective utilization of this medication.

Drug Interactions

A small arrow pointing down.

Tadalafil functions as a phosphodiesterase type 5 (PDE5) inhibitor frequently employed in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hyperplasia (BPH). When formulated as 25 mg/ml oral sublingual drops, tadalafil provides the benefit of rapid onset of action due to immediate absorption into systemic circulation via the oral mucosa. This method of administration proves particularly advantageous for patients who might struggle with conventional tablets or require a customized dosing regimen.

However, tadalafil has the potential to interact with various medications and substances, which could diminish its effectiveness or heighten the likelihood of adverse reactions. One of the most critical interactions involves nitrates, commonly prescribed for angina (chest pain). The concurrent use of tadalafil with nitrates can lead to a hazardous drop in blood pressure; thus, patients taking any form of nitrates should refrain from using tadalafil.

Alpha-blockers, prescribed for high blood pressure and BPH, can also cause blood pressure to plummet significantly when combined with tadalafil. Consequently, patients on alpha-blockers should be stable on their medication prior to initiating tadalafil, and tadalafil should be introduced at the lowest effective dose.

Medications prescribed for the treatment of HIV, particularly protease inhibitors, may elevate the levels of tadalafil in the bloodstream, potentially resulting in enhanced side effects. Similarly, certain antifungal treatments, such as ketoconazole and itraconazole, as well as certain antibiotics like erythromycin, can affect tadalafil’s metabolism.

Other blood pressure-affecting medications, including antihypertensives and vasodilators, should be approached with caution when a patient is prescribed tadalafil, as the combined impacts on blood pressure may be unpredictable and could lead to symptomatic hypotension.

Grapefruit juice is known to influence the metabolism of tadalafil, leading to increased exposure and a higher likelihood of side effects; therefore, patients should be advised to avoid grapefruit juice during treatment with tadalafil sublingual drops.

Additionally, alcohol consumption can increase the risk of experiencing side effects from tadalafil, such as dizziness and headache. It is recommended to limit or eliminate alcohol intake while taking this medication.

Patients must inform their healthcare provider of any and all medications, supplements, and herbal products they are taking prior to commencing tadalafil treatment to circumvent possible drug interactions. Moreover, prescribers should carefully assess the patient’s medication history to ensure that tadalafil is an appropriate and safe option in their treatment regimen.

If you have questions or require further data regarding the drug interactions associated with tadalafil 25 mg/ml oral sublingual drops, please contact us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is available to provide guidance and support to facilitate the safe and effective use of this medication.

How Does it Work

A small arrow pointing down.

Tadalafil operates as a phosphodiesterase type 5 (PDE5) inhibitor, a classification of medications frequently used to manage conditions such as erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). The mechanism through which tadalafil exerts its effects involves the inhibition of PDE5, an enzyme located in the smooth muscle cells of the corpus cavernosum in the penis and in the pulmonary vasculature. By inhibiting PDE5, tadalafil facilitates an increase in levels of cyclic guanosine monophosphate (cGMP), leading to the relaxation of smooth muscle and subsequently increased blood flow to target regions of the body. In the context of ED, this process culminates in improved erectile function by enhancing blood flow to the penis in response to sexual stimulation. Regarding PAH, tadalafil aids in relaxing and dilating the blood vessels in the lungs, which in turn lowers pulmonary blood pressure and ameliorates symptoms.

The tadalafil 25 mg/ml oral sublingual drops represent a specialized liquid formulation allowing for direct administration under the tongue. This delivery route presents several advantages. Sublingual absorption