Tadalafil, also popularly known under its brand name Cialis, is predominantly prescribed for the management of erectile dysfunction (ED), which refers to the inability to obtain or sustain an erection adequate for satisfactory sexual performance. In addition to its primary purpose, it serves to mitigate the symptoms of benign prostatic hyperplasia (BPH), a condition commonly marked by an enlarged prostate. Symptoms of BPH include urinary hesitancy, dribbling, a weak urine stream, and the sensation of incomplete bladder emptying. Moreover, Tadalafil (Adcirca) finds its application in enhancing exercise capacity in patients suffering from pulmonary arterial hypertension (PAH), a serious condition characterized by high blood pressure in the pulmonary arteries. Patients with PAH might experience symptoms such as shortness of breath, dizziness, and fatigue.
The drug falls within the category of medications known as phosphodiesterase type 5 (PDE5) inhibitors. Its primary mechanism of action is to enhance blood flow to the penis during sexual arousal, thus facilitating the attainment of an erection. In the context of PAH treatment, Tadalafil exerts its effect by relaxing blood vessels in the lungs, thereby promoting a more efficient blood flow. It is significant to note that Tadalafil does not serve as a cure for ED or BPH, nor does it amplify sexual desire. Additionally, it does not offer any protection against sexually transmitted infections, including HIV.
Tadalafil is formulated in tablet form for oral consumption and can be ingested regardless of meal timing. Patients have two primary methods of administration: as needed or on a daily basis. It is imperative for patients to follow their healthcare provider’s dosing instructions closely.
When utilized for ED treatment, Tadalafil is typically taken at least 30 minutes prior to sexual activity, with a maximum frequency of once a day. For individuals opting for daily usage, it can be consumed at any time without consideration of sexual activity timing. It is advisable to consult a healthcare provider to determine the most suitable regimen.
In treating BPH or PAH, Tadalafil is generally prescribed for daily administration. Patients are advised to take the entire prescribed dose at the same time each day, without splitting tablets. Consistency in timing is encouraged, and if transitioning from other BPH medications, healthcare providers may recommend a brief pause in those treatments prior to starting Tadalafil.
Dosage modifications may be warranted based on the individual's response to treatment and any side effects encountered. Ongoing dialogue with a healthcare provider is essential to ensure a safe and effective therapeutic experience.
Tadalafil may also be indicated for additional conditions not specifically detailed in this overview. For comprehensive information, please consult with a healthcare professional or pharmacist.
Before Taking Tadalafil
- Notify your healthcare team if you have any known allergies to Tadalafil, other medications, or any other ingredients contained in Tadalafil tablets.
- Discuss your current medication list with your healthcare provider, especially if you are using nitrates (such as nitroglycerin), as combining these drugs with Tadalafil can result in severe side effects.
- Inform your healthcare provider about any illicit drug usages that involve nitrates, as this combination can lead to serious interactions.
- Keep in mind that Tadalafil is marketed under the brand names Adcirca and Cialis, and only one formulation should be used at a time.
- It’s crucial to provide a complete list of medications you are currently consuming, inclusive of over-the-counter drugs, vitamins, and dietary supplements, to ensure safe prescribing and monitoring.
- Make your doctor aware of any pre-existing health conditions, particularly those that affect the heart, liver, or kidneys.
- If you are a female patient using Tadalafil for PAH, inform your healthcare provider if you are pregnant, planning to conceive, or breastfeeding.
- Prior to any surgical interventions, including dental procedures, it is important to notify your healthcare provider about your use of Tadalafil.
- Moderate your alcohol intake while taking this medication, as excessive consumption can heighten the risk of adverse effects.
- For those who have experienced severe adverse events during sexual activity, including chest pains, seeking immediate medical consultation is recommended.
- Inform any healthcare professional who treats you that you are currently using Tadalafil.
It is advisable to consult with your doctor regarding any dietary restrictions and the safety of consuming grapefruit while on Tadalafil.
If you miss a dose for ED treatment, take the missed pill as soon as you remember. If the next scheduled dose is near, skip the missed dose and return to your regular dosing routine. Never take two doses simultaneously.
If you miss a dose for PAH or BPH, take the missed dose promptly, but if your next dose is approaching, omit the missed one. Never double up on doses.
Potential Side Effects of Tadalafil
Like any medication, Tadalafil may produce side effects. Seek immediate medical attention if you experience any of the following persistent or severe adverse effects:
- Headaches
- Indigestion or heartburn
- Nausea
- Diarrhea
- Flushing of the skin
- Pain in the stomach, back, muscles, arms, or legs
- Coughing
Serious Side Effects
Should you experience any of the following serious conditions, seek urgent medical help:
- Sudden loss of vision
- Blurred vision
- Altered color perception
- Sudden loss of hearing
- Ringing in the ears
- Erection lasting longer than four hours
- Dizziness
- Chest pain
- Skin rashes or hives
- Difficulty in breathing or swallowing
- Swelling of the face, throat, tongue, lips, or extremities
- Severe skin reactions
Some individuals have reported an abrupt change in vision or hearing after taking Tadalafil or other PDE5 inhibitors. While the causal relationship remains unclear, if such occurrences arise, discontinue Tadalafil and consult a healthcare provider without delay.
Store Tadalafil in its original packaging, securely sealed, and out of reach from children's access. Keep the medication at room temperature, away from excessive heat and moisture (do not store in the bathroom).
Unused medications should be disposed of appropriately to prevent accidental ingestion by children or pets. Avoid flushing medications down the toilet. Consult your pharmacist regarding drug take-back programs or reach out to your local waste management for safe disposal advice.
In the instance of an overdose, immediately contact the poison control center at 1-800-222-1222 or visit poisonhelp.org. If someone is unconscious, has suffered a seizure, is experiencing difficulty in breathing, or cannot be awakened, call emergency services at 911 right away.
Make sure to attend all scheduled follow-up appointments with your healthcare provider to monitor your treatment progress and address any concerns.
Do not share your medication with others. For any questions regarding refills, please contact your pharmacist.
Maintain an updated list of all medications you are taking, including prescription and over-the-counter drugs, vitamins, and dietary supplements. Carry this list with you for medical appointments or emergencies.
- Adcirca®
- Cialis®
- Entadfi® (as a combination product containing finasteride and Tadalafil)