pronounced as (sil den' a fil)
Sildenafil, the active ingredient commonly associated with Viagra, is primarily prescribed for the treatment of erectile dysfunction (ED), which is defined by the difficulty in achieving or sustaining an erection adequate for engaging in sexual activity. Beyond ED, sildenafil is also utilized under the brand names Liqrev and Revatio, serving as an effective treatment for pulmonary arterial hypertension (PAH). This condition entails elevated blood pressure within the blood vessels leading to the lungs. By promoting relaxation of these blood vessels, sildenafil significantly improves blood circulation, ultimately leading to a reduction in symptoms such as breathlessness and fatigue.
It is essential to understand that while sildenafil aids in achieving an erection, it does not address the underlying causes of erectile dysfunction or enhance sexual desire. Additionally, sildenafil does not serve as a preventive measure against sexually transmitted infections, including HIV.
Sildenafil is offered in various formulations, notably tablets and liquid suspensions, which are intended for oral consumption. For those dealing with erectile dysfunction, the medication is generally taken on an as-needed basis, approximately one hour prior to planned sexual activity. However, it may effectively be utilized anywhere from 30 minutes to up to four hours before intercourse. The advised maximum dosage should not exceed one intake in a 24-hour period. Notably, sildenafil can be ingested with or without food, though it’s important to consider that a fatty meal may potentially delay its effectiveness.
If prescribed for PAH management, patients typically follow a dosing regimen that involves three times daily administration, either with food or on an empty stomach. Maintaining a consistent schedule is recommended for the best therapeutic outcome.
In addition to its primary indications for erectile dysfunction and pulmonary arterial hypertension, sildenafil may also be prescribed off-label for various other medical conditions. It is advisable to discuss these alternative uses with your healthcare provider for accurate guidance.
Before Taking Sildenafil
- Notify your doctor or pharmacist about any known allergies, particularly to sildenafil or its components.
- Be cautious, as certain medications may adversely interact with sildenafil, especially nitrates often used for chest pain. It is vital to provide your healthcare provider with a comprehensive list of all medications, including over-the-counter and herbal supplements.
- Discuss your complete medical history, especially if you suffer from heart conditions, have a history of stroke, or have liver, kidney, or bleeding disorders.
- Inform your healthcare provider if you are a smoker or have recently undergone surgery, as these factors may affect the appropriateness of sildenafil treatment.
- Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using sildenafil to ensure safety.
- Note that sildenafil is marketed under several brand names, including Liqrev, Revatio, and Viagra. It is advisable to consistently use only one brand at a time to avoid any potential complications.
Consult with your healthcare provider regarding dietary considerations, particularly the consumption of grapefruit, as it may interfere with the effects of sildenafil.
For patients using sildenafil to address erectile dysfunction, it is unlikely to miss a dosage, since it is utilized as required. For those using it for PAH, if you miss a dose, take it as soon as you recall unless it’s close to when your next dose is due. In this case, skip the missed dose and do not double up.
Possible Side Effects of Sildenafil
Sildenafil may result in a variety of side effects, ranging from mild to severe. It is critical to seek medical advice if you experience persistent or serious side effects:
- Commonly reported side effects can include headache, facial flushing, indigestion, nasal congestion, and visual changes.
- Serious side effects require immediate medical attention and include sudden vision loss, tinnitus (ringing in the ears), severe dizziness, chest pain, or erections lasting more than four hours.
Patients on sildenafil should be aware of reported instances of serious cardiovascular incidents, especially individuals with pre-existing heart conditions. Always have thorough discussions with your healthcare provider regarding the risks associated with sildenafil in managing erectile dysfunction or pulmonary arterial hypertension.
Store sildenafil in a cool, dry place at room temperature. It is essential to keep it in its original container, out of children’s reach, and to dispose of any unused medications responsibly—never flush them down the toilet.
If a sildenafil overdose is suspected, immediately contact a poison control center or seek emergency medical care. Overdose symptoms may include severe dizziness, fainting spells, or prolonged, painful erections.
Regular check-ups with your healthcare provider are crucial while undergoing treatment with sildenafil to monitor your overall health. Maintain an updated list of all medications and supplements you are taking to share with your healthcare team.
- Liqrev®
- Revatio®
- Viagra®