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Understanding Sildenafil
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What is Sildenafil?
Sildenafil, which is the generic equivalent of the well-known medication Viagra, is an oral prescription drug designed specifically for the treatment of male sexual dysfunction, also referred to as impotence or erectile dysfunction (ED). It is typically taken in tablet form before engaging in sexual activity and should not be taken more than once within a 24-hour period. Interestingly, sildenafil is also available in various formulations and plays a dual role in medical treatment, as it is employed to manage pulmonary arterial hypertension (PAH) in both males and females. It is crucial to remember that these different formulations must not be mixed or used interchangeably.
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How does sildenafil work?
Sildenafil functions as a phosphodiesterase-5 (PDE-5) inhibitor. When combined with sexual stimulation, it promotes an increased flow of blood to the penis, thereby assisting men in achieving and sustaining an erection. Importantly, the medication produces no effects in the absence of sexual stimulation, which distinguishes its mode of action in the treatment of erectile dysfunction.
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How to take sildenafil for best results
To maximize its effectiveness, sildenafil should be taken approximately one hour prior to sexual activity. However, the medication can be consumed at any time within a range of 30 minutes to four hours before the desired sexual encounter. It is important to take sildenafil only as needed and refrain from exceeding one dose in a 24-hour period. This medication can be administered with or without food, providing flexibility in its use.
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How long does sildenafil take to work?
This medication is effective for the treatment of erectile dysfunction only when sexual stimulation is present. Sildenafil typically begins to take effect in approximately 60 minutes, making it a reliable option for those seeking to improve their sexual performance.
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How long does sildenafil last?
Erections induced by sildenafil can persist for two to four hours. If an erection lasts longer than four hours, it is essential to seek immediate medical attention, as this may indicate a serious condition that requires professional intervention.
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What are the side effects of sildenafil?
Like all medications, sildenafil has the potential to cause side effects, and while many are mild, some may be more serious in nature. Commonly reported side effects include headache, flushing (a warm, red sensation typically affecting the face, neck, ears, or chest), nasal congestion, and indigestion. These side effects are usually temporary and improve as the medication dissipates from the system, although it is advisable to contact a healthcare provider if they persist or become bothersome.
Immediate medical attention is crucial if any severe side effects occur, such as sudden hearing loss or impairment, visual disruptions (including changes in color vision, blurred vision, or heightened sensitivity to light), a sudden drop in blood pressure, or an erection lasting longer than four hours. Rare but significant eye issues have been reported that may result in changes in sight, occasionally leading to temporary or permanent vision loss. There is also a small risk of cardiovascular events, such as an irregular heartbeat, heart attack, or stroke, especially among individuals with pre-existing heart conditions. It is vital to discuss your complete medical history with your Walgreens healthcare provider to determine if sildenafil is a safe option for you.
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How to get sildenafil for erectile dysfunction through Walgreens Virtual Care
During your Walgreens Virtual Healthcare appointment, your provider will evaluate your symptoms and explore potential treatment options with you. The healthcare professional will assess whether sildenafil tablets for erectile dysfunction are suitable for your specific needs, ensuring a personalized approach to your treatment.
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Frequently Asked Questions
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Is sildenafil available over the counter?
No, sildenafil cannot be purchased without a prescription. A valid prescription from a licensed healthcare provider is necessary to obtain this medication.
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Do you need a prescription for sildenafil?
Yes, you must have a prescription to access sildenafil. It is not classified as an over-the-counter medication.
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What drugs interact with sildenafil?
Drug interactions can affect the efficacy of your medications and may increase the risk of adverse side effects. Sildenafil can interact with various medications and over-the-counter products, including vitamins and dietary supplements. It's vital to discuss with your Walgreens healthcare provider and pharmacist any other medications or supplements you are currently taking before starting sildenafil to avoid potential complications.
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What are the differences between sildenafil and Viagra?
Sildenafil is the generic formulation of Viagra. Both medications share the same active ingredient and are indicated for the treatment of erectile dysfunction, providing similar therapeutic effects.
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Will insurance cover a sildenafil prescription?
In some cases, insurance plans may cover sildenafil for erectile dysfunction. It is recommended to verify with your insurance provider to determine if sildenafil is included under your plan's coverage.
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Does Walgreens offer the brand Viagra?
Yes, Walgreens Virtual Care provides access to both the brand-name Viagra and the generic sildenafil for the treatment of erectile dysfunction. Consult with your healthcare provider to establish if it is appropriate for you.
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Can sildenafil be taken with food or alcohol?
Sildenafil can be consumed with or without meals. However, it is advisable to limit alcohol consumption while taking sildenafil, as alcohol may enhance the risk of low blood pressure.
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Sildenafil vs. tadalafil: What’s the difference?
Both sildenafil (generic Viagra) and tadalafil (generic Cialis) are phosphodiesterase-5 (PDE-5) inhibitors that function similarly to treat erectile dysfunction. While both can be taken as needed at least 30 minutes before sexual activity, tadalafil may remain effective longer in your system. Consequently, lower-strength tadalafil options are available for daily use, regardless of sexual activity timing. It is crucial to never take both medications simultaneously and consult with your healthcare provider to decide which option is best for your needs.
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Sildenafil vs. Vardenafil: What’s the difference?
Sildenafil (generic for Viagra) and vardenafil (generic for Levitra) are both PDE-5 inhibitors used in the management of erectile dysfunction, working through a similar mechanism. Generally, vardenafil should be administered an hour prior to sexual activity, while sildenafil can be taken as soon as 30 minutes beforehand and up to four hours before engagement. Both medications have comparable durations of action and should be utilized on an as-needed basis, with a limit of one dose per day. Importantly, these medications should not be used concomitantly, and it is recommended to speak with your healthcare provider to determine the most suitable option for your condition.
References
1. Viagra (sildenafil citrate) tablets, for oral use. Package insert. Pfizer Labs. 2014.
2. Sildenafil: MedlinePlus drug information. MedlinePlus. Accessed February 19, 2025.
3. Cialis (tadalafil) tablets, or oral use. Package insert. Eli Lilly and Company. 2011.
4. Levitra (vardenafil hydrochloride) tablets, for oral use. Package insert. Bayer HealthCare Pharmaceuticals Inc. 2014.
Disclaimers
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Based on national averages. Actual times may vary.
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